5 EASY FACTS ABOUT PRO33 DESCRIBED

5 Easy Facts About pro33 Described

5 Easy Facts About pro33 Described

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, pharmacological rescue of your behavioral phenotypes will go a long way toward clarifying the molecular underpinnings in the psychological, social, and repetitive behaviors influenced by this mutation.

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When the role in the Pro33 variant has actually been studied within the periphery, the practical and biochemical outcomes of the mutation in the brain continue to be mysterious. During this study, we employed the KI mouse design, where the Pro32Pro33 variant of mouse integrin βthree is expressed within the endogenous pro33 casino integrin βthree locus (Oliver et al., 2014) to look at the effect of the mutation on the 5-HT system within the brain.

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An automated tail suspension test machine (Med Associates) was utilized to measure the period of behavioral immobility. Mice were being suspended through the tail with tape to the vertical aluminum bar connected to a pressure gauge.

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